Cryptographic functions have been commonly abused by malware developers to hide malicious behaviors, disguise destructive payloads, and bypass network-based firewalls. Now-infamous crypto-ransomware even encrypts victim’s computer documents until a ransom is paid. Therefore, detecting cryptographic functions in binary code is an appealing approach to complement existing malware defense and forensics. However, pervasive control and data obfuscation schemes make cryptographic function identification a challenging work. Existing detection methods are either brittle to work on obfuscated binaries or ad hoc in that they can only identify specific cryptographic functions. In this paper, we propose a novel technique called bit-precise symbolic loop mapping to identify cryptographic functions in obfuscated binary code. Our trace-based approach captures the semantics of possible cryptographic algorithms with bit-precise symbolic execution in a loop. Then we perform guided fuzzing to efficiently match boolean formulas with known reference implementations. We have developed a prototype called CryptoHunt and evaluated it with a set of obfuscated synthetic examples, well-known cryptographic libraries, and malware. Compared with the existing tools, CryptoHunt is a general approach to detecting commonly used cryptographic functions such as TEA, AES, RC4, MD5, and RSA under different control and data obfuscation scheme combinations.