Machine Learning (ML) has found it particularly useful in malware detection. However, as the malware evolves very fast, the stability of the feature extracted from malware serves as a critical issue in malware detection. The recent success of deep learning in image recognition, natural language processing, and machine translation indicates a potential solution for stabilizing the malware detection effectiveness. We present a color-inspired convolutional neural network-based Android malware detection, R2-D2, which can detect malware without extracting pre-selected features (e.g., the control-flow of op-code, classes, methods of functions and the timing they are invoked etc.) from Android apps. In particular, we develop a color representation for translating Android apps into rgb color code and transform them to a fixed-sized encoded image. After that, the encoded image is fed to convolutional neural network for automatic feature extraction and learning, reducing the expert’s intervention.We have run our system over 800k malware samples and 800k benign samples through our back-end (60 million monthly active users and 10k new malware samples per day), showing that R2-D2 can effectively detect the malware. Furthermore, we will keep our research results on http://R2D2.TWMAN.ORG if there any update.